Compatibility and System Requirements
MacOS versions can contain features to save the contents of the Documents folder in iCloud and to "optimize" storage by storing less-used files only in iCloud online. EndNote libraries stored in iCloud, even when stored on both the hard drive and online, are subject to corruption over time. If you choose to store your documents in iCloud, we suggest creating a separate folder in your home folder and saving your EndNote libraries there. Do not store EndNote libraries in iCloud or any other cloud-syncing folder, and do not store EndNote libraries in the Documents folder if you have selected the option to store documents in iCloud.
Tips for success:
Safari and EndNote
We recommend that you use Mozilla Firefox or Google Chrome as your browser when searching databases to export references to your EndNote Library. The Safari browser will always send the reference to the downloads folder first which means an extra step for you to put it in your EndNote Library.