Pharmacy Guide: Evidence-Based practice

1. Ask a question
   Converting the need for information (about prevention, diagnosis, prognosis, therapy, causation, etc) into an answerable question

2. Search and find information/evidence to answer question
   Tracking down the best evidence with which to answer that question 

3. Critically appraise the information/evidence
   Critically appraising that evidence for its validity (closeness to the truth), impact (size of the effect), and applicability (usefulness in our clinical practice) 

4. Implement and integrate appraised evidence with own clinical expertise and patient’s preferences
   Integrating the critical appraisal with our clinical expertise and with our patient's unique biology, values and circumstances 

5. Evaluate
   Evaluating our effectiveness and efficiency in executing Steps 1-4 and seeking ways to improve them both for next time 

Evidence-based medicine : how to practice and teach it EBM. - 3rd ed. / Sharon E. Strauss ... [et al.]. - Edinburgh ; New York : Elsevier/Churchill Livingstone, 2005.

This should be an ongoing process in clinical practice.

Also see: http://library.health.nt.gov.au/c.php?g=172510&p=1137931

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Answering Clinical Questions - Tutorials provided by the University of Western Australia on:

• How to formulate a clinical question
• How to find the best evidence
• How to appraise the evidence
• How to apply the evidence

Duke University (US) EBM Tutorial - An excellent, clearly set-out tutorial that:

• Defines EBM
• Identifies the parts of a well built clinical question
• Identifies EBM searching strategies to improve MEDLINE retrieval
• Identifies issues that determine the validity of the results of a study

University of Sydney Library Tutorial - This tutorial aims to clarify the process of searching for reliable medical evidence in four stages:

• Analysing information needs and developing answerable questions
• Selecting the most appropriate evidence and data source
• Formulating an effective strategy
• Practical database searching session